Study of Effective Factors in Cervical Cancer in Isfahan

ABSTRACT Cancer of the cervix is a common malignancy in females' genital tract. This is the third most common malignancy in females. The main object of this study was to determine the risk factors associated with cervical cancer. In this case-control study, from 282 cases, 87 patients with progressive disease were in the case group and 195 healthy women in the control group. Sampling method in the case group was a simple one and in the control group a randomized one. These two groups had the same age characteristics. This research was performed in "Sayed-Al-Shohada" and "Amin" hospitals. The data were analyzed by SPSS. The results showed that cervical cancer is related to age of first marriage (P= 0.0008, OR=5), number of delivery (P=0.0001, OR= 3.2) and contraceptive method used (oc pills). Results showed that in the group who used oral contraceptive pills for more than 6 years, O.R was 3.3 (P = 0.008). The weekly mean intercourse rate at the first, second, third, and fourth decades of marriage life in the case group was more than control (P = 0.001). Socioeconomical status differences were not significant in rural VS urban areas (P>0.05). There was a significant relationship between education in two groups (P=0.018). Pap smear test results were flales negative in about 15.5 percent of cases. Some of the above mentioned risk factors probably increase the cervical cancer incidence. We wish by performing more interventional programs designed to omit as much risk factors as possible, this incidence rate would be reduced.